报告题目：Role of the RNA exosome complex in regulation of gene expression in Arabidopsis via long ncRNAs
报 告 人：Julia Chekanova
Professor Julia Chekanova is coming from the University of Missouri and Guangxi University. She holds the BS/M.S. degree in Microbiology from Moscow State University and her PhD in Microbiology from the Institute of Microbiology of Russian Academy of Sciences. She joined the UMKC with academic experience being a Research Assistant professor at State University of NY and sabbatical in the laboratory of 2017 Nobel Prize Laureate Michael Rosbash. Professor Chekanova is an RNA biologist and uses plants and yeasts as primary model systems for her research, and is working on RNA-induced epigenetic phenomena as well as in genome organization.
Among Professor Chekanovabiggest scientific accomplishments are: (1) Discovery of RNA polyadenylation in prokaryotes, which demonstrated for the first time that RNA polyadenylation has important biological functions in prokaryotes, where it facilitates 3′–>5′RNA decay. (2) Her biggest contribution to the field of RNA biology, plant biology and the entire field of gene expression in eukaryotes was the discovery of pervasive transcription in plants. Thediscovery of pervasive transcription demonstrated that in eukaryotes, over 90% of the genome is transcribed and produces non-coding RNAs. As a result of this discovery, combined with current advances in high-throughput technologies, non-coding RNAs and particularly lncRNAs now represent an important new frontier in molecular genetics and molecular biology. Professor Chekanovaresearch had been published in such premiere journals as Proceedings of National Academy of Sciences, Cell,EMBO J, PLoSGenetics, Nuclear Acids Research, Current opinion in Plant Biology and others. Three of her publication were selected as must read papersby the Faculty of 1000. She is also the editor of the “Plant lncRNAs” book in the series of Methods in Molecular Biology (March 2019). Her research had been supported by multiple US federal grants (NSF, NIH, USDA, BARD) and Missouri state agricultural Board grant (MLSRB). She also serves as a Member of the Editorial Board of Scientific Reports.